Our Research Projects

Investigating toroidal nuclei's role in cancer.

Microscopic image showing a toroidal nucleus within a cancer cell.
Microscopic image showing a toroidal nucleus within a cancer cell.

Identification of the mechanisms by which autophagy protects against chromosomal instability in cancer cells

Studying how nuclear shape affects chromosome segregation.

Promotion of the toroidal nucleus as useful biomarker of chromosomal instability

Studying how nuclear shape affects chromosome segregation.

Funding

Decoding autophagy-mediated mitotic control for advanced cancer therapeutics

Reference: PID2024-155897OB-I00
Funding: Ministerio de Ciencia e Innovacion
Affiliate Institution: Universitat de Barcelona
From 01/09/2025 to 31/08/2028
PI: Caroline Mauvezin

Study of mitotic autophagy in cancer: a new therapeutic window

Reference: RYC2022-035576-I
Funding: Ministerio de Ciencia e Innovacion
Affiliate Institution: Universitat de Barcelona
From 01/09/2025 to 31/08/2028
PI: Caroline Mauvezin

Study of novel biomarkers for CIN-targeted breast cancer therapy (CALIBRATE)

Reference: LABAE222994MAUV
Funding: AECC Scientific Foundation
Affiliate Institution: Universitat de Barcelona
From 01/12/2022 to 30/05/2026
PI: Caroline Mauvezin

Cell Compartments: trafficking and signaling in health and disease (SGR)

Reference: 2017 SGR 01743
Funding: Ministerio de Economía y Competitividad (MINECO-JIN)
Affiliate Institution: Universitat de Barcelona
From 01/11/2021 to 31/10/2024
PI: Caroline Mauvezin

Study of the function of autophagy and lysosomes in mitosis and its implication to preserve from chromosomal instability to develop novel cancer combination therapy

Reference: PID2020-118768RJ-I00
Funding: Ministerio de Economía y Competitividad (MINECO-JIN)
Affiliate Institution: Universitat de Barcelona
From 01/11/2021 to 31/10/2024
PI: Caroline Mauvezin

Identification of a novel function of lysosomes in mitosis for cancer therapy

Reference: 799000
Funding: HORIZON 2020 Marie Sklodowska-Curie Actions
From 01/01/2019 to 31/12/2020
PI: Caroline Mauvezin

Technological Transfer

Evaluation of the efficiency of natural compounds for skin depigmentation based on their capacity to modulate autophagy

Reference: 311473
Funding: Bella Aurora Labs. S.A
From 15/12/2021 to 15/08/2022
PI: Caroline Mauvezin

Identification of compounds for skin depigmentation based on modulation of autophagy

Reference: 310921
Funding: Bella Aurora Labs. S.A
From 02/10/2020 to 02/02/2021
PI: Albert Tauler and Caroline Mauvezin